What can cause the appearance of wheals on the skin?

Wheals, which are raised, itchy areas on the skin, are often the result of an allergic reaction. When the body comes into contact with an allergen—such as certain foods, medications, or environmental factors—the immune system can overreact, leading to the release of histamines. This release causes blood vessels to dilate and fluid to accumulate in the surrounding tissues, resulting in the formation of wheals.

While skin infections can cause various types of rashes or irritation, they typically do not manifest as wheals. Sunburns cause damage to the skin without the characteristic raised structure seen in wheals. Friction can lead to irritation and possibly hives, but it is not a primary cause of wheals, which are more directly associated with allergic reactions. Thus, allergies are the most accurate trigger for the appearance of wheals on the skin.