What is a solid bump larger than 0.4 inches (1 centimeter) that can be easily felt called?

A nodule is characterized as a solid bump that exceeds 0.4 inches (1 centimeter) in diameter and is typically palpable under the skin. These growths can be found in various tissues and may be a sign of an underlying condition. Nodules can vary in their implications depending on their location and characteristics.

In contrast, a macule refers to a flat, distinct, discolored area of skin that is not raised, making it different from a nodule. A lesion is a more general term that encompasses any abnormal change in the structure of the skin or other tissues, and does not specify size or texture. A cyst is a closed sac-like structure that can be filled with liquid or semi-solid material, differing in both structure and often in texture from a nodule.

Therefore, the definition of a nodule aligns perfectly with the criteria given in the question, confirming it as the correct answer.