What is the term for the abnormal thickening of the stratum corneum?

The term that describes the abnormal thickening of the stratum corneum is hyperkeratosis. This condition occurs when there is an increased production of keratin, which is the protein that helps protect the skin. In hyperkeratosis, the outer layer of skin becomes significantly thicker, often resulting from various factors such as friction, chronic irritation, or certain skin conditions. Understanding hyperkeratosis is important because it can manifest in various forms, including calluses or other skin disorders, and can indicate underlying health issues.

Keratosis pilaris, although it involves the buildup of keratin, specifically affects hair follicles and leads to small, rough bumps on the skin rather than a generalized thickening of the stratum corneum. Dermatitis refers to inflammation of the skin, often resulting in redness and other symptoms, rather than a thickening of the skin layer. Hypopigmentation involves a decrease in skin pigment and does not relate to the thickness of the stratum corneum. Therefore, hyperkeratosis is the most precise term for the abnormal thickening of the outer layer of the skin.